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Diabetic Foot Infections: Toe to Toe

By Richard L. Oehler, MD

November 6th, 2023

Dr. Richard L. Oehler, MD, Professor of Medicine at the USF Morsani College of Medicine, presents this update on Diabetic Foot Infections (DFIs). Focusing on recent guidelines updates from 2023, Dr. Oeher discusses DFI epidemiology, pathophysiology, and Diabetic foot exam basics. He then goes on to review diabetic vascular disease and its role in the progression of diabetic foot complications. Dr. Oehler then reviews the workup of diabetic foot infections including imaging and physical examination findings. Lastly, the management of diabetic foot osteomyelitis is discussed including treatment strategies and prevention.

Pneumonia

By John Greene, MD

October 30th, 2023

Dr. John Greene, Professor of Medicine and Chief of Infectious Diseases at Moffitt Cancer Center and Research Institute, presents a review of Pneumonia in this podcast. He differentiates the different pneumonia types by lung pattern, distinguishing the likely etiologies in the categories of ground glass pnuemonia, consolidative infiltrates, small and large nodular pneumonia, and cavitary disease. The lecture is presented in a case-based format to facilitate retention of the information and for ease in learning. Noninfectious etiologies of lung infiltrates are also presented.

Antivirals and Antifungals in Cancer Patients

By Rod Quilitz, Pharm.D., BCOP

October 24th, 2023

Dr. Rod Quilitz, Lead Pharmacist and Antimicrobial Stewardship Program Coordinator at Moffitt Cancer Center and Research Institute, presents a comprehensive talk on the use of antifungal agents and antivirals in the Malignancy patient. Dr Quilitz begins by reviewing the mechanisms of action of different antifungal drug classes. He next discusses Polyene antifungals, azoles, echinocandins in order and includes information on their structure, indications, spectrum of action, dosing information, and toxicities. Lastly, Dr Quilitz discusses antivirals used in the treatment of Herpesvirus family infections, including acyclovir, ganciclovir, foscarnet, cidofovir, and others.

Dropping the MIC: Review of Updated Breakpoints and Implications on Clinical Practice

By Mellissa Albert, PharmD

October 17th, 2023

Melissa Albert, Infectious Diseases Pharmacy Resident, discusses the recent new literature regarding changes in the clinical breakpoints. Utilizing clinical cases, Dr. Albert demonstrates how to interpret antimicrobial susceptibility reports as well as how to design a patient-centered treatment regimen. Dr. Albert also discusses inducible AmpC-E resistance and how specific breakpoints have been changed for Aminoglycosides.

Malaria and Fever in the Returning Traveller

By Kami Kim, MD

October 10th, 2023

Dr. Kami Kim, Chief of the USF’s Division of Infectious Diseases and International Medicine, presents an update on Malaria and fever in the returning traveller. Dr. Kim begins her talk by presenting an overview of the tropical infections associated with a febrile presentation. She then discusses the work up if the returning traveller with fever, including essential elements of the history, physical exam, and laboratory workup. She then reviews the history of malaria and then moves on to malaria epidemiology. The life cycle of malaria is presented, and then the factors associated with transmission are reviewed. Malaria diagnostics are also discussed. Lastly, Dr. Kim closes by contrasting the distinctions between the individual malaria species (falciparum, malariae, ovale, knowlesi) and their clinical spectrums of disease.

Overview of Antibiotics

By Jose Montero, MD

October 5th, 2023

Dr. Jose Montero, Professor of Medicine at the Division of Infectious Diseases, Morsani College of Medicine, presents a basic review of anti-infective agents. Dr. Montero begins by discussing the initial assessment of antibiotic choice, related to broad versus narrow spectrum coverage, allergy assessement, and awareness of normal flora versus pathogens. Next, he discusses MIC interpretation and mechanisms of resistance. Dr. Montero then covers each of the major antibiotic classes, including cephalosporins, carbapenems, flouroquinolones, aminoglycosides, gloycopeptines, and oxazolidinones. Lastly, Dr. Montero discusses antibiotic agents used for the coverage of highly resistant bacteria. Cost information about antibiotic agents is also shared.

HIV and Malignancy

By Ana Velez, MD

August 22nd, 2023

Dr. Ana Velez, Professor of Medicine and Infectious Diseases Clinician at Moffitt Cancer Center and Research Institute, discusses the association between malignancies and Human Immunodeficiency Virus Infection. Dr. Velez begins by discussing that factors in HIV disease and stimulate the formation of cancers. Next, Dr. Velez discusses AIDS defining maligancies, including Kaposi sarcoma, Non-Hodgekin Lymphoma, and cervical cancer. Dr. Velez then discusses lung cancer and head and neck cancer in HIV disease, and speculates on the reasons for poorer outcomes in these patients. Lastly, state of the art therapies for malignancy treatment in HIV patients are discussed, including stem cell transplantation and CAR-T therapy.

Infections in Solid Organ Transplant Recipients

By Sally Alrabaa, MBBS

August 4th, 2023

Dr. Sally Alrabaa, Co-Director of Transplant Infectious Diseases at the Morsani College of Medicine, presents an overview of infection issues surrounding the solid organ transplant patient. Dr. Alrabaa differentiates specific infections based upon the early, medium, and late transplant periods. She then covers infections associated with certain specific immunosuppressive regimens. Next, the speaker discusses infections characteristic of different transplant types, including kidney, heart, liver, and lung transplants. Lastly, Dr. Alrabaa briefly touches upon Covid-19 and transplantation.

Essentials of Antibiotic Dosing

Dr. Kristen Zeitler, a pharmacist and pharmacotherapy specialist at Tampa General Hospital, discusses basic information about how to properly dose antimicrobial agents in hospital patients. Dr. Zietler begins by discussing the role that ID clinical pharmacist play in hospitals. She then compares and contrasts the differences between pharmacokinetics (PK) and pharmacodynamics (PD). The principles of pharmacokinetics are then covered, with regard to absorption, distribution, metabolism, and elimination. Next, PK/PD concepts are explored, especially as it relates to Vancomycin. Lastly, adjustment of dosing in renal insufficiency or dialysis is explored.

Basic Principles of Microbiology

By Suzane Silbert, PhD

July 17th, 2023

Dr. Suzanne Silbert, Microbiology Director for Tampa General Hospital, presents this introductory talk on the basics of the microbiology lab. Dr. Silbert begins with an overview of clinical microbiology, and then reviews the basic classification standards for bacterial organisms, viruses and fungi. She then goes on to discuss culture cultivation techniques, including the use of liquid, solid, or semi-solid media. The speaker then covers identification systems for bacterial organisms, including MALDI-TOF, Disk-Diffusion, and molecular diagnostic techniques. A robust question and answer session concludes the session