Dr. So reviews prosthetic joint infections, focusing on epidemiology, risk factors, classification, pathogenesis, and responsible microorganisms. The also discusses pre-operative evaluation. She touches upon the distinction between operative strategies, including singe stage and two stage procedures. Lastly, she discusses prevention in these patients.
Dr. Akoghlanian reviews several modern studies useful in the diagnosis of infectious diseases. In addition to blood cultures, Dr. Akoghlanian discusses urinary antigens, PCR/NAAT assays, multiplex panels, and Maldi-Tof/Mass Spectroscopy. Dr. Akoghlanian also speculates on future developments in infectious diseases diagnostics.
Dr. So reviews the phenomenon of beta lactam hypersensitivity. She discusses the different types of drug hypersensitivity, explains the risks for cross-reactivity between beta-lactams, touches upon strategies to avoid adverse drug reactions, and reviews penicillin and cephalosporin allergy testing. She closes by mentioning the ways that antimicrobial stewardship programs can address drug allergies.
Dr. Toney discusses the phenomenon of mass extinctions occuring over the history of life on our planet, and how it is believed we are currently in the sixth worldwide extinction. He speculates on its relevance in the context of human pathogens such as Clostridium difficile, multidrug resistant gram negative enteric bacteria, and on the persistance of gut microbiota. He closes by discussing potential future therapies for human diseases given the waning antimicrobial agent options we currently have to treat them.
Dr. Manuel Castro presents an update on the effects that climate change is having on infectious diseases as we approach the end of the second decade of the new millennium. He covers the impact that a warming climate is having on ecosystems that breed infectious pathogens as well as the vectors that carry them.
Dr. Quilitz discusses the risk factors behind neutropenic fever. He then discusses prominent bacterial, fungal, and viral pathogens which cause infections in the immunocompromised cancer patient. Lastly, he discusses antimicrobial options to prevent or treat opportunistic infections in these patients.
Dr. John Greene discusses different patterns of consolidation visible on lung imaging and the differential diagnosis for pneumonia in immunocompetent and immunocompromised patients. He reviews CT imaging for ground glass opacities, consolidation, nodular opacities, and nodular cavitary lesions on the lungs. He covers interstitial pulmonary fibrosis, pulmonary alveolar proteinosis, community acquired viral and bacterial pneumonia, fungal infections, and mycobacterial infections among others. He specifically discusses nocardia, mycobacterium avium complex and hypersensitivity pneumonitis. He then covers several cases studies and management strategies. His updated talk was originally presented in 2013.
Dr. Baluch introduces the audience to to concept of hematopoietic stem cell transplantation. She discusses the timeline for infections and the tools for their work-up, including antimicrobial drugs. She also reviews the current paradigm for the work-up of neutropenic fever, and the treatment of “common” ID issues. Lastly, she discusses useful infectious diseases resources for the clinician.