Dr. Toney discusses the phenomenon of mass extinctions occuring over the history of life on our planet, and how it is believed we are currently in the sixth worldwide extinction. He speculates on its relevance in the context of human pathogens such as Clostridium difficile, multidrug resistant gram negative enteric bacteria, and on the persistance of gut microbiota. He closes by discussing potential future therapies for human diseases given the waning antimicrobial agent options we currently have to treat them.
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