Finding a Cure for HIV: Reservoir Eradication

Joseph Paruolo, DO
Wednesday, May 6, 2015
Category: HIV/AIDS

Dr. Joseph Paruolo discusses the HIV reservoir, patients thought to be cured, and continuing efforts to cure HIV. Reservoirs include immunological cells, the brain, retinal cells, myocytes, adipose, kidneys, GI tract, epithelium, testes – which can be difficult for ART to penetrate. He discusses measuring the reservoir and viral load in an effort to detect cure rate. To date, only one person, Timothy Brown, has been confirmed to be cured, while several others thought to be cured but who had very low viral loads due to viral reservoirs.

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