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Urinary Tract Infections: Learning Through Three Cases

By Olga Klinkova, MD

February 5th, 2020

Dr. Olga Klinkova reviews the definitions and common facts regarding urinary tract infections. She differentiates between complicated and uncomplicated UTIs, upper and lower tract urinary tract infections, as well as the clinical features of pyelonephritis. She also discusses the management of MDRO-related urinary tract infections. The lecture is presented in a case-based format to help the learner improve their management skills through the discussion of typical patient-based scenarios.

Current Immunization Practice: The Role of Adult Vaccination

By John Toney, MD, FIDSA

January 27th, 2020

Dr. Toney presents an overview of adult vaccinations, focusing on the vaccines that are most important and relevant for the adult patient. He begins by discussing pneumococcal vaccines, whose guidelines can often be confusing because of the two different types of vaccines and their distinct administration schedules. He next talks about the influenza vaccine, differentiating the different types of vaccines, the efficacy of the flu shot, and potential future flu vaccine products. Next, he discusses the TDAP and the importance of receiving this vaccine given waning adult immunity for Pertussis. Dr. Toney also touches upon Shingles immunization and the significant advance of the recombinent shingles vaccine that is now available. Lastly, he discusses the MMR, Meningococcus, and Hepatitis vaccines.

Don’t Miss It: Ambulatory Care Infectious Diseases Emergencies

By John Toney, MD, FIDSA

January 15th, 2020

Dr. Toney, Professor of Medicine in the Division of Infectious Diseases at the University of South Florida, conducts a case-based discussion regarding Infectious diseases syndromes for which it is essential that a provider not miss the diagnosis in an ambulatory care setting. Dr. Toney initiates each case by presenting a case, then providing choices of possible answers, followed by clinical pearls relevant to the case. At the conclusion of this informative and interactive presentation, it is hoped that the audience will have a greater understanding of several critical ID ambulatory care emergencies that every provider needs to recognize.

Clinical Review of Three BMT Cases

By Aliyah Baluch, MD, Msc

January 6th, 2020

Dr. Aliyah Baluch, Chief BMT ID clinician at the Moffitt Cancer Center and Research Institute reviews 3 interesting BMT-related ID cases and offers insights into their management. From a lecture originally recorded in December, 2019.

Navigating Beta-Lactam Allergies

By Tiffany Ward

November 22nd, 2019

Dr. Ward begins her presentation by reviewing the impact of beta-lactam allergies on the healthcare system. She then discusses the classification system for the different types of hypersensitivity reactions. The significance of beta-lactam allergy cross reactivity is then mentioned. She goes on to explain how beta-lactam allergy testing is performed. Lastly, she identifies strategies to improve the documentation of beta-lactam allergy reporting.

 

Emerging Infections: Sexually Transmitted Infections

By Kami Kim, MD

November 15th, 2019

Dr. Kami Kim, Chief of Infectious Diseases at the University of South Florida College of Medicine, discusses an important subset of emerging infections: sexually transmitted diseases (STIs). She initially reviews the current epidemiology of STIs in the U.S. She differentiates the more common and less common STIs. She goes on to discuss risk factors for sexually transmitted infections. She focuses on Neisseria gonorrhea infections, and discusses epidemiology, drug resistance, and treatment changes. She closes by sharing information on the diverse syndromes associated with Chlamydia trachomatis, including genital ulcer disease, urethritis, and cervicitis, extragenital infections, and pelvic inflammatory disease, and shares general treatment strategies and pitfalls.

Community Acquired Pneumonia: Update on Diagnosis and Management

By Olga Klinkova, MD

October 30th, 2019

Dr. Olga Klinkova, Infectious Diseases Clinician at the Moffitt Cancer Center and Research Institute, discusses the recent updates to the diagnosis and management of community acquired pneumonia. Dr. Klinkova begins her talk by referring to the recently introduced IDSA-ATS guidelines, released in August, 2019. She then discusses updates in the microbiology of CAP, including the most likely organisms, the role of MRSA, atypicals and the significance of viral pathogens. She then mentions diagnostic modalities and the relevance of clinical prediction algorithms such as CURB-65 and the Pneumonia Severity Index (PSI). Treament considerations including outpatient versus inpatient, and inpatient non-severe versus inpatient severe management are also differentiated. Specific treatment agents and therapy durations are also mentioned. Lastly, she discusses options for the management of MRSA pneumonia and aspiration syndromes.

Future Diagnostics in Tuberculosis

By Ju Hee Katzman

October 15th, 2019

Dr. Ju Hee Katzman begins her lecture by discussing some basic epidemiology of Tuberculosis, a major killer worldwide and still a significant infectious cause of mobility in the U.S. Dr. Katzman reviews the traditional diagnostic modalities for diagnosing TB (including expectorated sputum samples for smear and culture). She then goes on to discuss specific molecular techniques for diagnosing TB that will play an increasingly larger role in the future. Lastly, she touches upon the ways in which AI (Artificial Intelligence) can be utilized to detect and treat active tuberculosis in settings where health provider availability is greatly challenged.

New Antimicrobials for Multidrug Resistant Organisms

By Harrison Bachmeier, PharmD

October 1st, 2019

Dr. Bachmeier presents an up-to-date review of newer-generation antimicrobials designed to be effective against infections with multiple drug-resistant pathogens. He first reviews the different types of extended-spectrum beta-lactamase (ESBL) resistance. He then discusses the significance of Carbapenemase-producing enterobacteriaceae and ESBL producing E coli, Klebsiella pneumonia, and Pseudomonas aeruginosa strains. Such organisms have become increased threats to our patients over the last two decades while new drug approvals have dwindled. Dr. Bachmeier reviews Ceftolozane-tazobactam, Ceftazidime-avibactam and their current indications. He then reviews Meropenem-vaborbactam and its utility in the treatment of Klebsiella pneumonia carbabenemase (KPC) infections. He then discusses imipenem-relebactam and its advantages in the treatment of MDR gram-negative infections. Lastly, he reviews plazomycin, eravacycline, and Cefiderocol.

Infectious Diseases: Evolution, Revolution, Heresy, Enlightenment?

By John T. Sinnott, MD

August 26th, 2019

Dr. Sinnott’s grand rounds presentation reflects upon the history of infectious diseases, from the late 1960’s, when the battle with infectious agents was felt to have been won, to the present age of widespread antimicrobial resistance, emerging pathogens, and the newer therapies of the “post-antibiotic era.” He focuses on genetic susceptibility, and how this has played a major role in infectious diseases outbreaks of the past. He also touches upon commercial “boutique” genetics services which offer to sequence an individual’s genome for ancestry and hereditary purposes. Lastly, he comments on the importance of the human microbiome to disease susceptibility and wellness.