Basic Immunology

By Anthony Cannella, MD

August 18th, 2022

Dr. Anthony Cannella, Infectious Diseases Clinician and Associate Professor with the Division of Infectious Diseases at the Morsani College of Medicine, presents a primer on basic immunology for clinicians. Dr. Cannella begins by drawing a distinction between innate and adaptive immunity. He then discusses the complement cascade, antimicrobial peptides, PAMPS, and DAMPS. Next, Dr. Cannella reviews individual components of the immune system, including neutrophils, eosinophils, macrophages, dendritic cells, and natural killer cells. Lastly, the remaining components of the immune system are covered, including B cells, immunoglobulins, and T cells and their function.

ID Management of Patients with Hematologic Malignancies and Stem Cell Transplants

By Olga Klinkova and Aliyah Baluch

August 4th, 2022

Dr. Olga Klinkova covers essential information regarding the management of infectious complications of hematologic malignancies. Topics covered include the initial evaluation of patients, neutropenic fever, neutropenic enterocolitis, and antimicrobial prophylaxis. Next, Dr. Baluch discusses ID management of stem cell transplants, CAR-T therapy, and when it is necessary to administer antimicrobial prophylaxis in these patients. The talks are from an Infectious Diseases Bootcamp for ID Fellows recorded in August 2022.

Infectious Diseases Emergencies

By Guy Handley, MD

August 4th, 2022

Dr. Guy Handley, Assistant Professor with the Division of Infectious Diseases at the Morsani College of Medicine, presents his talk on infectious diseases emergencies. He discusses a variety of different syndromes, including bacterial meningitis, neutropenic fever, bacteremia, malaria, and viral hemorrhagic fevers. The information is presented in a Q&A format. This talk is Part of the “Infectious Diseases Bootcamp” series for USF infectious Diseases fellows presented in August, 2022.

Infectious Complications of the Primary Immunodeficiencies

By Tuhina Cornelius, MD

July 26th, 2022

Dr. Tuhina Cornelius, senior infectious diseases fellow at the University of South Florida College of Medicine, reviews the primary immunodeficiencies in this podcast presentation. The speaker begins by presenting the basics regarding the differences between cellular and humoral immunity. She then discusses specific B cell and T cell related immune deficits. Dr. Cornelius then goes on to describe disorders of phagocytosis, motility, complement, and other miscellaneous syndromes. Lastly, the management of these disorders is reviewed.

Tuberculosis: The Great Imitator

By Suhel Sabunwala, MD

July 15th, 2022

Dr. Suhel Sabunwala, Senior Infectious Diseases fellow at the University of South Florida College of Medicine, presents an update on Tuberculosis, a legacy disease of mankind rich in history and very much still highly prevalent in the modern world. Dr. Sabunwala begins by discussing the history of tuberculosis. He then transitions to the current status of TB disease and its impact in the US and across the globe. He further discusses how TB and COVID-19 have interacted during the pandemic. Lastly, the speaker discusses updates in treatment and global targets for eradication.

Genitourinary Tract Infections: Update for 2022

By John Toney, MD, FIDSA

July 5th, 2022

Dr. John Toney, Professor of Medicine at the University of South Florida Division of Infectious Diseases, presents an update on Genitourinary tract infections. He begins the presentation by discussing the many manifestations of UTIs, from asymptomatic bacteriuria to cystitis to pyelonephritis. He then differentiates acute uncomplicated and acute complicated cystitis. Next, he discusses acute pyelonephritis, its management and treatment options. More information on the assessment of asymptomatic bacteriuria is also presented. Next, Dr. Toney transitions to discussing updates in the the management and treatment of STI’s including Gonorrhea, Chlamydia, and Syphilis with an emphasis on the recent guidelines updates.

Update on CMV and Treatment Options for 2022

By Aliyah Baluch, MD, Msc

May 19th, 2022

Dr. Aliyah Baluch, Program Director of the Infectious Diseases Transplant Program at the Moffitt Cancer Center and Research Institute, presents an update on CMV infections in the Immunocompromised host. She begins by discussing the basics of allogeneic stem cell transplantation, including pre-transplant screening and what differentiates a “high risk transplant.” She then provides some background information on Cytomegalovirus, including its clinical manifestations in susceptible patients. Next, Dr. Baluch conveys the phases of infection in stem cell transplant, and identifies the high risk period for CMV disease to typically occur. She then discusses CMV diagnosis, antiviral therapies, and CMV prophylaxis strategies. Dr. Baluch closes by discussing CMV drug resistance as well as several information resources useful in the management of CMV-infected patients.

Neglected Tropical Diseases: Part II

By Ana Sikora, MD

May 12th, 2022

Dr. Ana Sikora, Infectious Diseases Fellow at the University of South Florida Division of Infectious Diseases, presents a review of lesser known tropical infectious diseases syndromes. Dr. Sikora begins by discussing the epidemiology of tropical diseases, and then prioritizes the most important ones based upon WHO categorization. Syndromes discussed includes Drucunculiasis, lymphatic filariasis, Onchocerciasis, soil transmitted helminths, and Schistosomiasis. Lastly, the process by which international organizations such as the WHO coordinate efforts to control or eradicate these syndromes is briefly discussed.

LGBTQ+ Health 101

By Alberto Contreras, MD

May 5th, 2022

Dr. Alberto Contreras, Infectious Diseases Fellow at the University of South Florida College of Medicine, presents a primer on medical issues associated with lesbian, bisexual, gay and transgender patients. Dr Contreras begins by discussing the spectrum of those individuals who identify with the LGBTQ community. He then differentiates sexual orientation and gender identity. Next, Dr Contreras covers basic gender grammar. He next discusses health care disparities occurring among this group of patients. Other topics covered during the presentation include substance abuse, care guidelines for LGBT patients, and the effects of hormone therapy.

Dynamic Duos: Dual Therapy for Gram Positive Infections

By Austin Morrison, Pharm.D

April 19th, 2022

Dr. Austin Morrison, Infectious Diseases/Antimicrobiaql Stewardship pharmacist at Moffitt Cancer Center and Research Institute, presents a lecture on the use of dual therapy in gram positive infections. Dr. Morrison begins by discussing dual therapy for Staphylococcus aureus infections, and then transitions to discuss similar therapy for Enterococcus faecalis. Dr. Morrison shares information on mechanisms of action, the rationale for dual beta lactams, and the use of daptomycin with beta-lactams.

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