Dr. Castro reviews the epidemiology of anal squamous cell carcinoma, a significant malignancy in HIV positive men who have sex with men (MSMs). He also reviews risk factors, classification systems, the disease’s association with Human Papilloma Virus (HPV), screening strategies, and management after diagnosis
Archives
Infections Associated with Freshwater and Saltwater Exposure
Using Echocardiography in Staphylococcus Aureus Bacteremia
Top Ten Lesser Known Contemporary Outbreaks
In a question and answer format, Dr. Oehler covers 10 recent outbreaks that are lesser known, either because of their regional nature, small number of cases, or simply because they lack a well-known champion. Examples of these include the Heartland virus, Australian Bat Lyssavirus, and Enterovirus 068.
Zika and Emerging Arboviruses in the Americas
Dr. Sandra Gompf highlights the recent emergence of several mosquito-borne arboviruses in the Caribbean and South American continent, including Dengue virus, Chikungunya, and Zika virus. In particular, she examines Zika and the factors responsible for its development on our continent. Dr. Gompf also discusses Zika epidemiology, risk factors, clinical manifestations, treatment, and prevention.
Cholera
HIV and Malignancy: Understanding Oncogenesis in the Age of ART
A Primer on Respiratory Infections in the Immunosuppressed
Invasive Fungal Infections in the Immunocompromised Host
Dr. Aliyah Baluch focuses on the work-up and treatment of invasive fungal infections in the immunosuppressed patients. Fungal infections have high morbidity and mortality, but can be hard to clinically diagnose. Invasive infections occur in ICU, Diabetes Mellitus, and immunocompromised patients. Dr. Baluch covers both aspects of Candida and non-Candida species infections, including risk factors, symptoms, prognosis, work-up, and treatment in patients with immunosuppressed patients. She includes a review of fungal structure and the mechanism of action of the drug classes used to treat them – Echinocandins, Polyenes, and Triazoles. She covers timelines that indicate which species to expect during each stage of immunosuppression and with different mechanisms of immunosuppression, including differences between stem cell and solid organ transplants. Biomarkers for treatment and international patterns of drug resistance are also discussed.
Overview of Bone and Joint Infections
Yanina Pasikhova, clinical pharmacist at Moffitt Cancer Center, presents this talk about bone and joint infections – osteomyelitis, septic arthritis, prosthetic joint infection. Ms. Pasikhova goes over case studies while focusing on different organisms expected in acute vs. chronic infections, route of infections, indications for empiric treatment, and work-up for infections. Infections can occur via hematogenous spread due to risk factors like IV Drug Use, hemodialysis, or immunocompromise, or contiguous from surgery, open fractures, burns, and soft tissue infections. She discusses diagnostics, including best practices for cultures, and indications for imaging studies. Finally, she discusses treatment – while there are no official guidelines for Osteomyelitis, but historically IV antibiotics are used. She reviews the literature which compares oral and IV antibiotics and which antibiotics should be used for different infections.


