Dr. Ramon Sandin reviews the identification, diagnosis, and management of infectious fungi. He covers yeasts and molds that are clinically relevant to the practicing clinician, including systemic dimorphic species of Histoplasma, Blastomyces, Coccidioides, Paracoccidiodes, Sporothrix, Penicillum, and molds involved in chromoblastomycosis. He also discusses subcutaneous mycoses and opportunistic infections. He reviews laboratory diagnosis, histopathologic stains, and cultures. Affiliated with Moffitt Cancer Center, he also discusses mycoses in the setting of immunocompromise or malignancy.
Recorded in November 2014, Dr. Vivian Vega presents an update on the 2014-2016 West African Ebola outbreak adapted for both healthcare workers and patients. She speaks about the epidemiology, clinical manifestations and the effect of the outbreak on other public health issues such as malaria and TB. She also talks about the implications of the outbreak in the global community, the possibility of pandemic spread, and reviews four patients diagnosed with Ebola in the United States. Finally, Dr. Vega discusses risk assessment for patients exposed to the virus as well as its diagnosis and management. As the last major global outbreak, a look back to 2014 adds some insight into how we are managing the current Coronavirus pandemic.
Dr. Beata Casanas presents an update on the epidemiology, stages, diagnosis, and management of tuberculosis. While the absolute number of TB cases has decreased, the rate of decrease has slowed. Dr. Casanas also touches on considerations required for multi-drug resistant TB. She discusses different diagnostic tests, including PPD, sputum studies, and interferon-gamma release assays, and the differences between active and latent TB. She also discusses TB co-infection in HIV-infected patients, as both infections independently accelerate the progression of the other.
Dr. Toney discusses recent developments in the management and treatment of sepsis.
Dr. Aliyah Baluch, an infectious diseases physician at Moffitt Cancer center discusses common infections that affect cancer patients. She reviews epidemiology, risk stratification for neutropenic fever, monoclonal antibodies, and antibiotic resistance in the setting of the immunocompromised cancer patient. She also reviews management of neutropenic fever, common pathogens, and selected syndromes – nodular pneumonia and ecthyma gangrenosum.
Linda Cheung, PharmD, speaks about the treatment of Clostridium difficile infections. She provides a background on C. difficile epidemiology, pathogenesis, risk factors (antibiotics and proton pump inhibitors), clinical manifestations (diarrheal disease, pseudomembranous colitis, toxic megacolon), diagnostic laboratory tests (PCR, EIA toxin assay, cytotoxins, stool culture), and management. She also discusses probiotic prophylaxis, new antimicrobials indications for C. difficile, IVIG use, and stool transplants. Finally, she discusses future therapies in development and infection control – the importance of proper handwashing.
Dr. Lysenia Mojica discusses the recent Ebola outbreak in West Africa. She speaks about the history and characteristics of the Filoviridae and discusses Ebola virus in particular. Ebola vectors are unknown, though thought to be carried by bats, and transmission of the highly virulent and stable virus can occur parenterally and by physical contact. She goes over clinical manifestations, risk factors, laboratory findings, and management and containment strategies. Finally, she discusses global implications of the West Africa outbreak.
Dr. Rey Rivera, infectious diseases fellow at the USF College of Medicine discusses a case of MERS and the implications of the 2014 MERS Coronavirus outbreak. The 2020 SARS CoV-2 Coronavirus shares similarities with the SARS-CoV and MERS, as all are Betacoronaviruses. He provides an overview of the infection, viral characteristics, epidemiology, presentation, diagnosis, and management. He also goes over screening criteria from the CDC and recommendations for people traveling to endemic areas such as Saudi Arabia. MERS outbreaks are still ongoing in the Middle East as of early 2020. Though the podcast was recorded in 2014, the specifics of MERS are worth revisiting in the shadow of the 2020 Coronavirus pandemic.