Dr. Klinkova reviews CSF device-associated infections, an important potential source of morbidity for neurosurgical patients. She first discusses risk factors, and then transitions to discuss the pathogenesis and microbiology of shunt infections. Next, she reviews the typical clinical presentation of patients who present with the syndrome, and then discusses diagnostic pearls for identifying patients with CSF device infections. She then reviews the management of these patients including the principles of antibiotic selection. Lastly, Dr. Klinkova covers CSF device-associated infection prophylaxis.
Dr. Sandin provides a general overview of identification techniques for Mycobacterial organisms. He discusses and outlines classification systems for the Mycobacteria that are human pathogens. He then discusses laboratory stains that are useful in identifying Mycobacteria and reviews other diagnostic methods which have become essential to Mycobacterial species identification, including the various nucleic amplification-based methods. Various pathology pearls of Mycobacterial identification are also mentioned. Lastly, he discusses two clinical cases involving acid fast organisms.
Dr. Oehler conducts a lively quiz session regarding infectious diseases historical figures and events dating from 600 BC to 1900. In this fast paced and humorous podcast, listeners are exposed to the accomplishments of infectious disease titans such as Hippocrates, Anton Van Leewenhoek, Ignaz Semmelweis, and John Snow. After listening to this podcast, participants will have a much broader sense of the legacy of infectious diseases history as well as some other fascinating trivia that will entertain and amaze!
To enjoy the companion lecture to this one regarding 20th Century ID events, please watch this presentation:
Dr. Oehler reviews infections of the diabetic foot. He begins by introducing the concept of a multidisciplinary team as essential to the management of these patients. He then describes the current epidemiology of diabetes and diabetic foot ulcers. He also discusses Charcot arthropathy and how it occurs . Annual diabetic foot exams are also crucial to these patients, and Dr. Oehler also reviews proper techniques and what to ask/examine. He also covers diabetic peripheral vascular disease, diagnostic imaging modalities, wound management, and the proper empiric antibiotic regimens and durations of therapy. Lastly, he discusses prevention techniques necessary to avoid recurrent ulceration.
Dr. Jamie Morano reviews sexually transmitted infections among MSMs (men who have sex with men). She discusses current sexually transmitted infection screening, testing, and treatment guidelines for the group. The use of preexposure prophylaxis for MSMs is also introduced, and includes information on eligibility and an implementation strategy for patients. Lastly, Dr. Morano touches upon HIV screening and rapid treatment approaches to care.
Dr. Jamie Morano reviews HIV infection. She starts out by presenting up to date statistics about the current epidemiology of HIV infection across the US and Florida. She then goes on to discuss the HIV life cycle, and how various antiretroviral treatments appear to interact with the virus at different points of the viral reproductive process. HIV resistance mechanisms are also addressed. Lastly, she shares her recommendations on strategies useful to selecting an ideal antiretroviral regimen for an HIV positive patient.
Dr. Baluch reviews the topic of invasive fungal infections (IFIs) in individuals who undergo hematopoietic stem cell transplantation (HCST). The author begins by reviewing risk factors for IFIs. She then discusses what constitutes an IFI. She differentiates infections caused by yeasts versus those due to molds, and discusses the assessment and management of invasive candida disease. Next, Dr. Baluch discusses non candida molds, including aspergillus, fusarium, and Mucor as well as atypical pathogens such as Pneumocystis. She closes with a discussion of antifungal therapy and what constitutes the ideal fungal agent.
Dr. Ward reviews basic concepts about antimicrobial drug interactions. She begins by discussing the basic classification scheme, and then moves on to discuss several commonly recognized adverse drug interactions, as well as some that are commonly forgotten. She also reviews the topic of QT drug prolongation, the interaction between daptomycin and statins, as well as the most relevant azole interactions. She reviews serotonergic interactions, especially with linezolid. Lastly, she reviews the interaction between valproic acid and carbapenems. And the best reference sources for reviewing adverse drug interactions with antimicrobials are also discussed.
Dr. Chugtai reviews the family of Viral Hemorrhagic Fevers. He starts out by discussing transmission factors and major common symptoms for the class of disorders. He then covers the Bunyaviridae, including Hantavirus Pulmonary Syndrome and Rift Valley Fever. Dr. Chugtai then mentions the hemorrhagic fevers, including Ebola and Marburg viruses. Other hemorrhagic fevers dicussed includes Nipah virus disease and Hendra virus disease. Lastly, he discusses the flaviviruses, including Tick-borne encephalitis (TBE).