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Infections of the Eye, Part I

By John Toney, MD, FIDSA

February 2nd, 2024

In a two part series, Dr. John Toney, Professor of Medicine at the University of South Florida Division of Infectious Diseases, reviews various infectious syndromes involving the eye. For Part One, Dr. Toney initially reviews the anatomy of the eye. Next, he reviews blepharitis, conjunctivitis, and diseases of the cornea. Dr. Toney concludes the lecture by discussing microbial keratitis, HSV keratitis, and acanthamoeba keratitis. For part II, please refer to the upcoming presentation posting next week.

Mold Pneumonias in Oncology Patients

By Guy Handley, MD

January 26th, 2024

Dr. Guy Handley, Assistant Professor at the USF Morsani Division of Infectious Diseases and International Medicine, presents a talk on Fungal pneumonias in immunocompromised patients. Dr. Handley begins by discussing the differential diagnosis of pneumonia, and then an overview of the most common types of mold pneumonias by pathogen. He then shares a case presentation of a mold pneumonia and discusses options in a question and answer format utilizing PollEv. Next, Dr. Handley focuses on Aspergillosis , then Zygomycosis, and compares and contrasts the two. Diagnostic and treatment options are explored for the invasive molds. Lastly, future directions in mold therapy are mentioned, including Fosmanogepix, ibrexafungerp, Rezafungin, and others.

Nocardia and Actinomycosis

By Richard L. Oehler, MD

January 19th, 2024

Dr. Richard Oehler, Professor of Medicine at the Division of Infectious Diseases and International Medicine, Morsani College of Medicine at USF, presents this overview of Nocardia and Actinomyces, two closely-related gram positive filamentous rods which have distinct differences. In his presentation, Dr. Oehler initially covers Nocardiosis, followed by Actinomycosis, and compares and contrasts both and how they produce human infection. Topics covered for both infections include their taxonomy, epidemiology, types of patients infected, infectious syndromes, potential complications, recommended therapies, and duration of treatment. At the end of the talk both Nocardiosis and Actinomycosis are directly compared to help summarize the important learning points presented.

Non-Tuberculous Mycobacterial Infections, Part 1

By Anthony Cannella, MD

January 12th, 2024

Dr. Anthony Cannella, Associate Professor of Medicine at the University of South Florida Division of Infectious Diseases, presents this update on nontuberculous mycobacterial (NTM) infections. Dr. Cannella begins by discussing the taxonomy of nontuberculous mycobacteria. Next, he reviews epidemiology including the common methods of transmission of the infection. He then describes the immunological factors that confer increased susceptibility for certain individuals. Laboratory growth characteristics are also reviewed. Dr. Cannella then reviews the most significant species of NTM producing disease in humans. He begins by describing Mycobacterium avium complex, and then discusses M. kansasii, M. xenopii, M. haemophilum, S. szulgai, and M. marinum. Clinical cases are presented throughout the talk to help with information retention and provide specific clinical examples.

Surgical Prophylaxis

By Shuchi Pandya, MD

January 8th, 2024

Dr. Shuchi Pandya, infectious diseases clinician with the ID Associates of Tampa Bay, presents an update in the use of antimicrobials for surgical prophylaxis. Dr Pandyla begins by clarifying the definition of a surgical site infection. She then differentiates the categories of surgical procedures in terms of clean, clean contaminated, contaminated, and dirty procedures and their typical microbial characteristics. She then discusses other aspects of antimicrobial prophylaxis, including timing, duration, and surgery-specific variations. Specific recommendations for GI Surgery, OB-Gyn, orthopedic, breast, and spinal surgery are also discussed in a fast paced presentation.

Aspergillus, Mucor, and Sporothrix Infections

By Aliyah Baluch, MD, Msc

November 20th, 2023

Dr. Aliyah Baluch, Program Lead for Bone Marrow Transplant Infectious Diseases at Moffitt Cancer Center and Research Institute, reviews Important opportunistic fungal pathogens of relevance to the stem cell transplant and immunocompromised patient. Dr. Baluch beings by discussing the pharmacologic options for aspergillus treatment and their individual mechanisms of action. Next, through a case-based format, she reviews specific scenarios related to fungal infections with Aspergillus, Mucor, and Sporothrix. Lastly, new agents in the antifungal pipeline are discussed, and a robust question and answer session closes the presentation.

Protozoal Diseases

By Jacqueline Sherbuk, MD

November 13th, 2023

Dr. Jackie Sherbuk, Assistant Professor at the Division of Infectious Diseases and International Medicine, Morsani College of Medicine, reviews the most important protozoal infections affecting humans. Dr. Sherbuk begins by discussing Entomaeba histolytica, the agent of amoebic colitis, amoebic liver abscess, and dysentery. Next, Dr. Sherbuk elaborates on Leishmaniasis, differentiates visceral, mucosal, and cutaneous disease and and discusses diagnosis and treatment. Next, the speaker discusses Trypanosoma Cruzei (Chagas disease), including epidemiology, geographc distribution, life cycle, clinical manifestations, and the differences seen in immunocompromised persons. She closes by covering old and new world trypanosomiasis. Several case studies are also presented to help test the learner’s retention of the presented information.

Diabetic Foot Infections: Toe to Toe

By Richard L. Oehler, MD

November 6th, 2023

Dr. Richard L. Oehler, MD, Professor of Medicine at the USF Morsani College of Medicine, presents this update on Diabetic Foot Infections (DFIs). Focusing on recent guidelines updates from 2023, Dr. Oeher discusses DFI epidemiology, pathophysiology, and Diabetic foot exam basics. He then goes on to review diabetic vascular disease and its role in the progression of diabetic foot complications. Dr. Oehler then reviews the workup of diabetic foot infections including imaging and physical examination findings. Lastly, the management of diabetic foot osteomyelitis is discussed including treatment strategies and prevention.

Pneumonia

By John Greene, MD

October 30th, 2023

Dr. John Greene, Professor of Medicine and Chief of Infectious Diseases at Moffitt Cancer Center and Research Institute, presents a review of Pneumonia in this podcast. He differentiates the different pneumonia types by lung pattern, distinguishing the likely etiologies in the categories of ground glass pnuemonia, consolidative infiltrates, small and large nodular pneumonia, and cavitary disease. The lecture is presented in a case-based format to facilitate retention of the information and for ease in learning. Noninfectious etiologies of lung infiltrates are also presented.

Antivirals and Antifungals in Cancer Patients

By Rod Quilitz, Pharm.D., BCOP

October 24th, 2023

Dr. Rod Quilitz, Lead Pharmacist and Antimicrobial Stewardship Program Coordinator at Moffitt Cancer Center and Research Institute, presents a comprehensive talk on the use of antifungal agents and antivirals in the Malignancy patient. Dr Quilitz begins by reviewing the mechanisms of action of different antifungal drug classes. He next discusses Polyene antifungals, azoles, echinocandins in order and includes information on their structure, indications, spectrum of action, dosing information, and toxicities. Lastly, Dr Quilitz discusses antivirals used in the treatment of Herpesvirus family infections, including acyclovir, ganciclovir, foscarnet, cidofovir, and others.