Treatment of Clostridium Difficile Infection: Old Treatments and New Strategies

Linda Cheung, PharmD
Monday, June 16, 2014
Category: Bacterial Infections, GI Infections, Hospital Infections

Linda Cheung, PharmD, speaks about the treatment of Clostridium difficile infections. She provides a background on C. difficile epidemiology, pathogenesis, risk factors (antibiotics and proton pump inhibitors), clinical manifestations (diarrheal disease, pseudomembranous colitis, toxic megacolon), diagnostic laboratory tests (PCR, EIA toxin assay, cytotoxins, stool culture), and management. She also discusses probiotic prophylaxis, new antimicrobials indications for C. difficile, IVIG use, and stool transplants. Finally, she discusses future therapies in development and infection control – the importance of proper handwashing.

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